Jonathan Ipsaro
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Allostery Illuminated: Harnessing AI and Machine Learning for Drug Discovery
ACS Medicinal Chemistry Letters ·
August 2024
Maria-Jesus Blanco
,
Melissa J. Buskes
,
Rajiv G. Govindaraj
,
Jonathan J. Ipsaro
,
Joann E. Prescott-Roy
,
Anil K. Padyana
Cite
DOI
Evolutionary adaptation of an HP1-protein chromodomain integrates chromatin and DNA sequence signals
eLife ·
July 2024
Lisa Baumgartner
,
Jonathan J. Ipsaro
,
Ulrich Hohmann
,
Dominik Handler
,
Alexander Schleiffer
,
Peter Duchek
,
Julius Brennecke
Cite
DOI
Manipulating PTPRD function with ectodomain antibodies
Genes and Development ·
September 2023
Zhe Qian
,
Dongyan Song
,
Jonathan J. Ipsaro
,
Carmelita Bautista
,
Leemor Joshua-Tor
,
Johannes T.-H. Yeh
,
Nicholas K. Tonks
Cite
DOI
Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation
Cell ·
August 2023
Seung Cho Lee*
,
Dexter W. Adams*
,
Jonathan J. Ipsaro
*
,
Jonathan Cahn*
,
Jason Lyn
,
Hyun-Soo Kim
,
Benjamin Berube
,
Viktoria Major
,
Joseph P. Calarco
,
Chantal LeBlanc
,
Sonali Bhattacharjee
,
Umamaheswari Ramu
,
Daniel Grimanelli
,
Yannick Jacob
,
Philipp Voigt
,
Leemor Joshua-Tor
,
Robert A. Martienssen
Cite
DOI
ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation
Nature Cell Biology ·
January 2023
Yuan Gao
,
Xue-Yan He
,
Xiaoli S. Wu
,
Yu-Han Huang
,
Shushan Toneyan
,
Taehoon Ha
,
Jonathan J. Ipsaro
,
Peter K. Koo
,
Leemor Joshua-Tor
,
Kelly M. Bailey
,
Mikala Egeblad
,
Christopher R. Vakoc
Cite
DOI
OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage
Nature ·
May 2022
Xiaoli S. Wu
,
Xue-Yan He
,
Jonathan J. Ipsaro
,
Yu-Han Huang
,
Jonathan B. Preall
,
David Ng
,
Yan Ting Shue
,
Julien Sage
,
Mikala Egeblad
,
Leemor Joshua-Tor
,
Christopher R. Vakoc
Cite
DOI
Developmental roles and molecular mechanisms of Asterix/GTSF1
WIREs RNA ·
February 2022
Jonathan J. Ipsaro
,
Leemor Joshua-Tor
Cite
DOI
Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons
Cell Reports ·
March 2021
Jonathan J. Ipsaro
,
Paul A. O’Brien
,
Shibani Bhattacharya
,
Arthur G. Palmer III
,
Leemor Joshua-Tor
Cite
DOI
Tryp-N: A Thermostable Protease for the Production of N-terminal Argininyl and Lysinyl Peptides
Journal of Proteome Research ·
April 2020
John P. Wilson*
,
Jonathan J. Ipsaro
*
,
Samantha N. Del Giudice
,
Nikita Saha Turna
,
Carla M. Gauss
,
Katharine H. Dusenbury
,
Krisann Marquart
,
Keith D. Rivera
,
Darryl J. Pappin
Cite
DOI
Decoding the 5' nucleotide bias of PIWI-interacting RNAs
Nature Communications ·
February 2019
Chad B. Stein
,
Pavol Genzor
,
Sanga Mitra
,
Alexandra R. Elchert
,
Jonathan J. Ipsaro
,
Leif Benner
,
Sushil Sobti
,
Yijun Su
,
Molly Hammell
,
Leemor Joshua-Tor
,
Astrid D. Haase
Cite
DOI
Proteases for the production of N-terminal argininyl-and lysinyl-peptides and methods of use in protein analysis
US Patent ·
August 2017
Darryl J. Pappin
,
John P. Wilson
,
Jonathan J. Ipsaro
Cite
Rapid generation of drug-resistance alleles at endogenous loci using CRISPR-Cas9 indel mutagenesis
PLoS One ·
February 2017
Jonathan J. Ipsaro
,
Chen Shen
,
Eri Arai
,
Yali Xu
,
Justin B. Kinney
,
Leemor Joshua-Tor
,
Christopher R. Vakoc
,
Junwei Shi
Cite
DOI
NSD3-Short Is an Adaptor Protein that Couples BRD4 to the CHD8 Chromatin Remodeler
Molecular Cell ·
December 2015
Chen Shen
,
Jonathan J. Ipsaro
,
Junwei Shi
,
Joseph P. Milazzo
,
Eric Wang
,
Jae-Seok Roe
,
Yutaka Suzuki
,
Darryl J. Pappin
,
Leemor Joshua-Tor
,
Christopher R. Vakoc
Cite
DOI
From guide to target: molecular insights into eukaryotic RNA-interference machinery
Nature Structural & Molecular Biology ·
January 2015
Jonathan J. Ipsaro
,
Leemor Joshua-Tor
Cite
DOI
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
Nature ·
November 2012
Jonathan J. Ipsaro
*
,
Astrid D. Haase*
,
Simon R. Knott
,
Leemor Joshua-Tor
,
Gregory J. Hannon
Cite
DOI
Structurally similar but functionally diverse ZU5 domains in human erythrocyte ankyrin
Journal of Molecular Biology ·
April 2012
Mai Yasunaga
,
Jonathan J. Ipsaro
,
Alfonso Mondragón
Cite
DOI
Reporter protein-targeted probes for magnetic resonance imaging
Journal of the American Chemical Society ·
October 2011
Renee C. Strauch
,
Daniel J. Mastarone
,
Preeti A. Sukerkar
,
Ying Song
,
Jonathan J. Ipsaro
,
Thomas J. Meade
Cite
DOI
Crystal structure and functional interpretation of the erythrocyte spectrin tetramerization domain complex
Blood ·
June 2010
Jonathan J. Ipsaro
,
Sandra L. Harper
,
Troy E. Messick
,
Ronen Marmorstein
,
Alfonso Mondragón
,
David W. Speicher
Cite
DOI
Structural basis for spectrin recognition by ankyrin
Blood ·
May 2010
Jonathan J. Ipsaro
,
Alfonso Mondragón
Cite
DOI
Structures of the spectrin-ankyrin interaction binding domains
Blood ·
May 2009
Jonathan J. Ipsaro
,
Lei Huang
,
Alfonso Mondragón
Cite
DOI
Molecular epitopes of the ankyrin-spectrin interaction
Biochemistry ·
July 2008
Jonathan J. Ipsaro
*
,
Lei Huang*
,
Lucy Gutierrez
,
Ruby I. MacDonald
Cite
DOI
A draft of protein interactions in the malaria parasite P. falciparum
Journal of Proteome Research ·
April 2007
Stefan Wuchty
,
Jonathan J. Ipsaro
Cite
DOI
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